I too am interested in any gene Defects I see from prior post that heart Conditions it happens that I have a non cureable gentic defect called left Ventrical non compaction cardiomyopathy. I also have a cyst on my brain. This all could be conquinadental as my first Alkire is Sarah Alkire that Married John Samuel McCauley this is pretty far back. They are my direct line as well. Does anyone know the Alkire Hypogroup? Do you have any death Certificates for this line? I would be interested in what past down this line.